Wednesday, January 28, 2009

Movement of the Iron-Sulfur Head Domain of Cytochrome bc1 Transiently Opens the Catalytic Qo Site for Reaction with Oxygen.
Borek A, Sarewicz M, Osyczka A.
Biochemistry. 2008 Oct 29; [Epub ahead of print]
PMID: 18956890

Recent article

On the Mechanism of Quinol Oxidation at the QP Site in the Cytochrome bc1 Complex: STUDIED USING MUTANTS LACKING CYTOCHROME bL OR bH
Shaoqing Yang, He-Wen Ma, Linda Yu, and Chang-An Yu
J. Biol. Chem. 2008; 283(42): p. 28767-28776

Recent article

Stigmatellin Induces Reduction of Iron-Sulfur Protein in the Oxidized Cytochrome bc1 Complex
Buddha Gurung, Linda Yu, and Chang-An Yu
J. Biol. Chem. 2008; 283(42): p. 28087-28094

Recent article

Stefano Ff Torriani, Patrick C Brunner, Bruce A McDonald, and Helge Sierotzki
QoI resistance emerged independently at least 4 times in European populations of Mycosphaerella graminicola.
Pest Manag Sci 2 Oct 2008.

Recent article

Demonstration of Short-lived Complexes of Cytochrome c with Cytochrome bc1 by EPR Spectroscopy: IMPLICATIONS FOR THE MECHANISM OF INTERPROTEIN ELECTRON TRANSFER
Marcin Sarewicz, Arkadiusz Borek, Fevzi Daldal, Wojciech Froncisz, and
Artur Osyczka
J. Biol. Chem. 2008; 283(36): p. 24826-24836 Open Access

Recent article

The Yeast Aac2 Protein Exists in Physical Association with the Cytochrome bc1-COX Supercomplex and the TIM23 Machinery
Mary K. Dienhart and Rosemary A. Stuart
Mol. Biol. Cell. 2008; 19(9): p. 3934-3943

Recent article

Intrinsic curvature properties of photosynthetic proteins in chromatophores.
DE Chandler, J Hsin, CB Harrison, J Gumbart, and K Schulten
Biophys. J., September 15, 2008; 95(6): 2822-36.

Recent paper

Mechanisms of resistance to QoI fungicides in phytopathogenic fungi.
D Fernandez-Ortuno, JA Tores, A de Vicente, and A Perez-Garcia
Int Microbiol, March 1, 2008; 11(1): 1-9.

Sunday, June 8, 2008

Recent Article

The mechanism of mitochondrial superoxide production by the cytochrome bc1 complex.
Stefan Drose and Ulrich Brandt
J. Biol. Chem., June 3, 2008

In-depth review from Urbana

The Q-cycle reviewed: How well does a monomeric mechanism of the bc1 complex account for the function of a dimeric complex?

Antony R. Crofts, J. Todd Holland, Doreen Victoria, Derrick R.J. Kolling, Sergei A. Dikanov, Ryan Gilbreth, Sangmoon Lhee, Richard Kuras and Mariana Guergova Kuras

Biochimica et Biophysica Acta (BBA) - Bioenergetics
Article in Press, Corrected Proof
DOI 10.1016/j.bbabio.2008.04.037

Monday, May 26, 2008

New Atovaquone-resistance mutations:

Josephine E. Siregar, Din Syafruddin, Hiroyuki Matsuoka, Kiyoshi Kita and Sangkot Marzuki
Mutation underlying resistance of Plasmodium berghei to atovaquone in the quinone-binding-domain 2 (Qo2) of the cytochrome b gene

Parasitology International Volume 57,229-232

Saturday, May 10, 2008

Recent article:

Soluble Variants of Rhodobacter capsulatus Membrane-anchored Cytochrome cy Are Efficient Photosynthetic Electron Carriers

Yavuz Ozturk, Dong-Woo Lee, Sevnur Mandaci, Artur Osyczka, Roger C. Prince, and Fevzi Daldal

J. Biol. Chem. 2008; 283(20): p. 13964-13972

Recent article:

Cytochrome bc1-cy Fusion Complexes Reveal the Distance Constraints for Functional Electron Transfer Between Photosynthesis Components

Dong-Woo Lee, Yavuz Ozturk, Artur Osyczka, Jason W. Cooley, and Fevzi Daldal
J. Biol. Chem. 2008; 283(20): p. 13973-13982

Saturday, April 19, 2008

Methods paper-

Methods Mol Biol. 2008;432:65-81.
Click here to read
Preparation of Respiratory Chain Complexes from Saccharomyces cerevisiae Wild-Type and Mutant Mitochondria : Activity Measurement and Subunit Composition Analysis.

Lemaire C, Dujardin G.

CNRS, Centre de Génétique Moléculaire, Gif sur Yvette, France.

Highest resolution bc1 structure; cyt c bound; asymmetric dimer

Related Articles, Links
Click here to read
Structure of complex III with bound cytochrome c in reduced state and definition of a minimal core interface for electron transfer.

Solmaz S, Hunte C.

University of Leeds, Leeds LS2 9JT.

Monday, February 18, 2008

Possible arrangement of respiratory complexes in supercomplex

Schäfer E, Dencher NA, Vonck J, Parcej DN.
Three-dimensional structure of the respiratory chain supercomplex I(1)III(2)IV(1) from bovine heart mitochondria.
Biochemistry. 2007 Nov 6;46(44):12579-85

Sunday, February 10, 2008

Redox-dependent inhibitor binding, implications for conformational switch

Domain movement of iron sulfur protein in cytochrome bc1 complex is facilitated by the electron transfer from cytochrome bL to bH

Xiaowei Cen, Linda Yu and Chang-An Yu

FEBS Letters 582 (2008) 523-526